Recommended TVUS Screening Thresholds May Miss Endometrial Cancer in Black Women

Published by W Butcher on

Adherence to current clinical guidelines for the evaluation of postmenopausal bleeding may result in systematic underdiagnosis of endometrial cancer (EC) in Black women, according to a study published online July 15 in JAMA Oncology. Kemi M. Doll, M.D., from the University of Washington in Seattle, and colleagues compared the performance of recommended transvaginal ultrasonography (TVUS) endometrial thickness (ET) thresholds as a screening method to prompt endometrial biopsy according to race. The analysis included a simulated retrospective cohort (367,073 Black and White women with postmenopausal bleeding) based on data from the Surveillance, Epidemiology, and End Results national cancer registry (2012 to 2016), the U.S. census, and published estimates of ET distribution and fibroid prevalence.

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