Aspirin May Reduce Risk for CRC, But Only Among Certain Older Adults
New research suggests that initiating aspirin use in older patients is not associated with a lower risk of colorectal cancer in these individuals. Nevertheless, the pooled analysis of two cohort studies found that people who used aspirin before 70 years of age and continued into their 70s or later had a reduced risk of colorectal cancer. Reporting in a recent issue of JAMA Oncology, a multi-center team of investigators explained that aspirin is recommended for the prevention of colorectal cancer among adults between 50 and 59 years of age. Nevertheless, the recent ASPREE trial found conflicting results, and suggested a lack of benefit – and perhaps even possible harm – among older adults who take aspirin for this purpose.