The IMF-funded iStopMM study (Iceland Screens, Treats, or Prevents Multiple Myeloma) is the largest study of its kind, with a record-setting 80,759 participants. A cancer of the bone marrow plasma cells, multiple myeloma is always preceded by a condition called MGUS, in which an abnormal protein appears in the blood. Read more…
The CIBMTR® (Center for International Blood and Marrow Transplant Research®) announces the launch of a large observational study, done in collaboration with the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) to understand the safety, efficacy, and durability of responses to COVID-19 vaccines in patients with hematological malignancies and non-malignant Read more…
An American Cancer Society (ACS) review of cancer prevention and early detection measures for 2018 and 2019 in the United States shows mixed progress. Smoking prevalence during this time was at an historic low, partly because most people who ever smoked have quit. But obesity rates remained high, and cancer Read more…
BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160), a global biotechnology company focused on developing and commercializing innovative medicines worldwide, today announced that the Phase 3 RATIONALE 309 trial of its anti-PD-1 antibody tislelizumab combined with chemotherapy versus placebo combined with chemotherapy as a first-line treatment for patients with recurrent or metastatic nasopharyngeal Read more…
Today, the U.S. Food and Drug Administration approved Rybrevant (amivantamab-vmjw) as the first treatment for adult patients with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations. The FDA also approved the Guardant360 CDx (Guardant Health Inc.) as Read more…
Using donated umbilical cord blood, researchers from City of Hope National Medical Center in Los Angeles created an off-the-shelf chimeric antigen receptor (CAR) natural killer (NK) cell therapy that prolonged life with minimal side effects in a mouse model of metastatic human pancreatic cancer. The novel therapy, which targets prostate Read more…
By identifying a protein that disrupts the interplay between two key genetic drivers of pancreatic cancer, researchers from the University of Texas MD Anderson Cancer Center significantly dampened metastasis in preclinical studies with cell lines, genetic mouse models, and human pancreatic tumor tissue. According to results presented during the annual Read more…
BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160), a global biotechnology company focused on developing and commercializing innovative medicines worldwide, today announced that the U.S. Food and Drug Administration (FDA) has accepted a supplemental new drug application (sNDA) for BRUKINSA® (zanubrutinib) for the treatment of adult patients with marginal zone lymphoma (MZL) who have received at Read more…
A new study finds breast cancer survivors in general have higher risk of new cancer diagnosis compared to healthy individuals. The article, which appears in CANCER, states that compared to the general population in the United States, the risk of new cancer diagnoses among survivors was 20% higher for those with Read more…
Bristol-Myers Squibb Company (NYSE: BMY) and Agenus Inc. (NASDAQ: AGEN) today announced that they have entered into a definitive agreement under which Bristol Myers Squibb will be granted a global exclusive license to Agenus’ proprietary bispecific antibody program, AGEN1777, that blocks TIGIT and a second undisclosed target. AGEN1777 is an Fc-enhanced antibody in late Read more…