This study evaluated the cost-effectiveness of prophylactic cranial irradiation compared with magnetic resonance imaging (MRI) surveillance in this patient population. Cost-effectiveness of the treatment approaches were based on currently available evidence and in the context of the proposed Centers for Medicare & Medicaid Services alternative payment model. A Markov state transition model was developed to compare MRI surveillance alone vs prophylactic cranial irradiation for extensive-stage SCLC. Medicare reimbursement data from 2019 was used to dictate cost estimates. The incremental cost-effectiveness ratio (ICER) was used to compare strategies with effectiveness in quality-adjusted life years (QALYs). The willingness-to-pay threshold was $100,000 per QALY gained.
Radiation Oncologists Met With Congressional Leaders to Reverse CMS Cuts and Provide Equal Access to Care
Radiation oncologists met with Congress to urge leaders to consider how the Medicare and Medicaid Services (CMS) proposal to make significant cuts to radiation oncology facilities could be detrimental to the survival of patients with Read more…
FDA Approves Neoadjuvant Pembrolizumab Combination for Early TNBC Indication
The FDA granted approval to the supplemental biologics license application (sBLA) for pembrolizumab (Keytruda) as neoadjuvant therapy for patients with high-risk early-stage triple-negative breast cancer (TNBC) when given in combination with chemotherapy followed by single-agent Read more…
Recommended TVUS Screening Thresholds May Miss Endometrial Cancer in Black Women
Adherence to current clinical guidelines for the evaluation of postmenopausal bleeding may result in systematic underdiagnosis of endometrial cancer (EC) in Black women, according to a study published online July 15 in JAMA Oncology. Kemi M. Read more…