With 80,000 Participants, the Largest Study of Its Kind Is the First to Evaluate the Benefits of..
Dec 19, 2023
The IMF-funded iStopMM study (Iceland Screens, Treats, or Prevents Multiple Myeloma) is the largest study of its kind, with a record-setting 80,759 participants. A cancer of the bone marrow plasma cells, multiple myeloma is always preceded by a condition called MGUS, in which an abnormal protein appears in the blood. Doctors do not currently screen asymptomatic individuals for this blood cancer precursor. The iStopMM study examines the potential benefits versus the potential harms of screening for MGUS. The study’s leader, Dr. Sigurdur Kristinsson of the University of Iceland, compared screening for precancerous myeloma to screening currently done for precancerous cervical cancer and breast cancer. “Understanding the epidemiologic, genetic, and immunologic factors that go along with an increased risk of myeloma’s progression could open the door to early intervention efforts in high-risk patients and possible preventive strategies,” he said. “This would improve overall survival and quality of life for patients worldwide.”
Radiation Oncologists Met With Congressional Leaders to Reverse CMS Cuts and Provide Equal Access to Care
Radiation oncologists met with Congress to urge leaders to consider how the Medicare and Medicaid Services (CMS) proposal to make significant cuts to radiation oncology facilities could be detrimental to the survival of patients with Read more…
FDA Approves Neoadjuvant Pembrolizumab Combination for Early TNBC Indication
The FDA granted approval to the supplemental biologics license application (sBLA) for pembrolizumab (Keytruda) as neoadjuvant therapy for patients with high-risk early-stage triple-negative breast cancer (TNBC) when given in combination with chemotherapy followed by single-agent Read more…
Recommended TVUS Screening Thresholds May Miss Endometrial Cancer in Black Women
Adherence to current clinical guidelines for the evaluation of postmenopausal bleeding may result in systematic underdiagnosis of endometrial cancer (EC) in Black women, according to a study published online July 15 in JAMA Oncology. Kemi M. Read more…